ITA8164
ITA8164
ITA8164
from
$526.00
Price in reward points: 526
- Catalog: ITA8164
- Gene/Protein: EBI3
- Product Description: Immunotag™ EBI3 Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein EBI3 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:1000-3000 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen A synthesized peptide derived from human EBI3 Specificity EBI3 Antibody detects endogenous levels of total EBI3 Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name EBI3 Accession No. Q14213 Alternate Names cytokine receptor; EBI3; EBV induced gene 3 protein; EBV-induced gene 3 protein; Epstein Barr virus induced 3; Epstein Barr virus induced gene 3; Epstein Barr virus induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein; IL 27 subunit beta; IL 27B; IL-27 subunit beta; IL-27B; IL27 subunit; IL27 subunit beta; IL27B; IL27B_HUMAN; IL35 subunit; interleukin 27 subunit beta; Interleukin-27 subunit beta; Description Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 25 kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | EBI3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human EBI3 |
| Specificity | EBI3 Antibody detects endogenous levels of total EBI3 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | EBI3 |
| Accession No. | Q14213 |
| Alternate Names | cytokine receptor; EBI3; EBV induced gene 3 protein; EBV-induced gene 3 protein; Epstein Barr virus induced 3; Epstein Barr virus induced gene 3; Epstein Barr virus induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein; IL 27 subunit beta; IL 27B; IL-27 subunit beta; IL-27B; IL27 subunit; IL27 subunit beta; IL27B; IL27B_HUMAN; IL35 subunit; interleukin 27 subunit beta; Interleukin-27 subunit beta; |
| Description | Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 25 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |