ITA8317
ITA8317
- Catalog: ITA8317
- Gene/Protein: SCN1A
- Product Description: Immunotag™ Na+ CP type I alpha Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | Na+ CP type I alpha |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human Na+ CP type I alpha |
| Specificity | Na+ CP type I alpha Antibody detects endogenous levels of total Na+ CP type I alpha |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | SCN1A |
| Accession No. | P35498 |
| Alternate Names | HBSC II; HH1; hNaN; hNE-Na; hPN3; KIAA1356; MED; NAC1; NAC2; NAC3; NENA; Neuroendocrine sodium channel; Peripheral nerve sodium channel 3; Peripheral nerve sodium channel 5; Peripheral sodium channel 1; PN1; PN3; PN5; SCN1; SCN10A; SCN11A; SCN12A; SCN1A; SCN2A; SCN2A1; SCN2A2; SCN3A; SCN4A; SCN5A; SCN8A; SCN9A; Sensory neuron sodium channel 2; SkM1; SNS2; Sodium channel protein brain I subunit alpha; Sodium channel protein brain II subunit alpha; Sodium channel protein brain III subunit alpha; Sodium channel protein cardiac muscle subunit alpha; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type 1 subunit alpha; Sodium channel protein type 10 subunit alpha; Sodium channel protein type 11 subunit alpha; Sodium channel protein type 2 subunit alpha; Sodium channel protein type 3 subunit alpha; Sodium channel protein type 4 subunit alpha; Sodium channel protein type 5 subunit alpha; Sodium channel protein type 8 subunit alpha; Sodium channel protein type 9 subunit alpha; Sodium channel protein type II subunit alpha; Sodium channel protein type III subunit alpha; Sodium channel protein type IV subunit alpha; Sodium channel protein type IX subunit alpha; Sodium channel protein type V subunit alpha; Sodium channel protein type VIII subunit alpha; Sodium channel protein type X subunit alpha; Sodium channel protein type XI subunit alpha; Voltage-gated sodium channel subtype III; Voltage-gated sodium channel subunit alpha Nav1.1; Voltage-gated sodium channel subunit alpha Nav1.2; Voltage-gated sodium channel subunit alpha Nav1.3; Voltage-gated sodium channel subunit alpha Nav1.4; Voltage-gated sodium channel subunit alpha Nav1.5; Voltage-gated sodium channel subunit alpha Nav1.6; Voltage-gated sodium channel subunit alpha Nav1.7; Voltage-gated sodium channel subunit alpha Nav1.8; Voltage-gated sodium channel subunit alpha Nav1.9; |
| Description | Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. Plays a key role in brain, probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neurons induces pain without neurogenic inflammation and produces hypersensitivity to mechanical, but not thermal stimuli. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 228 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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