ITA8513
ITA8513
- Catalog: ITA8513
- Gene/Protein: RECK
- Product Description: Immunotag™ RECK Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | RECK |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human RECK |
| Specificity | RECK Antibody detects endogenous levels of total RECK |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | RECK |
| Accession No. | O95980 |
| Alternate Names | hRECK; Membrane anchored glycoprotein (metastasis and invasion); RECK; RECK protein; RECK_HUMAN; Reversion inducing cysteine rich protein with Kazal motifs; Reversion-inducing cysteine-rich protein with Kazal motifs; ST15; Suppression of tumorigenicity 15 (reversion inducing cysteine rich protein with kazal motifs); Suppressor of tumorigenicity 15; Suppressor of tumorigenicity 15 protein; |
| Description | Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 106 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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