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ITA8555

ITA8555-2
ITA8555-1
ITA8555-2
ITA8555-1
ITA8555
  • Gene/Protein: ERCC6
  • Product Description: Immunotag™ ERCC6 Antibody
280.0000
Price in reward points: 280

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Immunotag™ ERCC6 Antibody
Antibody Specification
Datasheet

Target Protein ERCC6
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,ELISA
Recommended Dilution WB 1:1000-3000 IHC 1:200
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen A synthesized peptide derived from human ERCC6
Specificity ERCC6 Antibody detects endogenous levels of total ERCC6
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name ERCC6
Accession No. Q03468
Alternate Names 4732403I04; ARMD 5; ARMD5; ATP dependent helicase ERCC6; ATP-dependent helicase ERCC6; C130058G22Rik; CKN 2; CKN2; Cockayne syndrome B protein; Cockayne syndrome group B protein; Cockayne syndrome protein CSB; COFS; COFS1; CS group B correcting; CSB; DNA excision repair protein ERCC 6; DNA excision repair protein ERCC-6; ERCC 6; ERCC6; ERCC6_HUMAN; Excision repair cross complementing rodent repair deficiency, complementation group 6; OTTHUMP00000019581; RAD26; Rad26 homolog; UVSS1;
Description Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 168 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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