ITA8738
ITA8738
- Catalog: ITA8738
- Gene/Protein: ITFG2
- Product Description: Immunotag™ ITFG2 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | ITFG2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human ITFG2 |
| Specificity | ITFG2 Antibody detects endogenous levels of total ITFG2 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | ITFG2 |
| Accession No. | Q969R8 |
| Alternate Names | Integrin alpha FG GAP repeat containing 2; Integrin alpha FG GAP repeat containing protein 2; Integrin-alpha FG-GAP repeat-containing protein 2; ITFG 2; ITFG2; ITFG2_HUMAN; MDS 028; MDS028; OTTHUMP00000161190; RGD1311944; Uncharacterized hematopoietic stem/progenitor cells protein MDS028; |
| Description | As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 49 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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