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ITA9030

ITA9030
ITA9030
ITA9030
ITA9030
ITA9030
from
$526.00
Price in reward points: 526
  • Catalog: ITA9030
  • Gene/Protein: BRAP
  • Product Description: Immunotag™ BRAP Antibody

Available Options

Immunotag™ BRAP Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein BRAP
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:1000-3000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen A synthesized peptide derived from human BRAP
Specificity BRAP Antibody detects endogenous levels of total BRAP
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name BRAP
Accession No. Q7Z569
Alternate Names 3010002G07Rik; BRAP2; BRCA1 associated protein; EC 6.3.2.; Galectin 2 binding protein; IMP; Impedes mitogenic signal propagation; Renal carcinoma antigen NY REN 63; RING finger protein 52; RNF52; zgc:92894;
Description Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 67 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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