ITA9043
ITA9043
ITA9043
from
$526.00
Price in reward points: 526
- Catalog: ITA9043
- Gene/Protein: KCNMB3
- Product Description: Immunotag™ KCNMB3 Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein KCNMB3 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:1000-3000 Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen A synthesized peptide derived from human KCNMB3 Specificity KCNMB3 Antibody detects endogenous levels of total KCNMB3 Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name KCNMB3 Accession No. Q9NPA1 Alternate Names BK channel subunit beta 3; BK channel subunit beta-3; BKbeta 3; BKbeta3; Calcium activated potassium channel beta 3 subunit; Calcium activated potassium channel subfamily M subunit beta 3; Calcium activated potassium channel subunit beta 3; Calcium-activated potassium channel; Calcium-activated potassium channel subunit beta-3; Charybdotoxin receptor subunit beta 3; Charybdotoxin receptor subunit beta-3; EG435726; Gm5707; Hbeta 3; Hbeta3; K(VCA)beta 3; K(VCA)beta-3; KCMB3_HUMAN; KCNMB 2; KCNMB 3; KCNMB2; KCNMB3; KCNMBL; Large conductance voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit; Maxi K channel subunit beta 3; Maxi K channel subunit beta-3; Potassium channel, calcium-activated large conductance, subfamily M, beta member 3; Potassium large conductance calcium activated channel beta 3 subunit; Potassium large conductance calcium activated channel subfamily M beta member 3; Slo beta 3; Slo-beta-3; subfamily M subunit beta-3; Description Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Alters the functional properties of the current expressed by the KCNMA1 channel. Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA. Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations. In contrast, isoform 1 does not induce detectable inactivation of KCNMA1. Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 32 kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
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| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | KCNMB3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human KCNMB3 |
| Specificity | KCNMB3 Antibody detects endogenous levels of total KCNMB3 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | KCNMB3 |
| Accession No. | Q9NPA1 |
| Alternate Names | BK channel subunit beta 3; BK channel subunit beta-3; BKbeta 3; BKbeta3; Calcium activated potassium channel beta 3 subunit; Calcium activated potassium channel subfamily M subunit beta 3; Calcium activated potassium channel subunit beta 3; Calcium-activated potassium channel; Calcium-activated potassium channel subunit beta-3; Charybdotoxin receptor subunit beta 3; Charybdotoxin receptor subunit beta-3; EG435726; Gm5707; Hbeta 3; Hbeta3; K(VCA)beta 3; K(VCA)beta-3; KCMB3_HUMAN; KCNMB 2; KCNMB 3; KCNMB2; KCNMB3; KCNMBL; Large conductance voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit; Maxi K channel subunit beta 3; Maxi K channel subunit beta-3; Potassium channel, calcium-activated large conductance, subfamily M, beta member 3; Potassium large conductance calcium activated channel beta 3 subunit; Potassium large conductance calcium activated channel subfamily M beta member 3; Slo beta 3; Slo-beta-3; subfamily M subunit beta-3; |
| Description | Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Alters the functional properties of the current expressed by the KCNMA1 channel. Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA. Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations. In contrast, isoform 1 does not induce detectable inactivation of KCNMA1. Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 32 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |