ITA9169
ITA9169
- Catalog: ITA9169
- Gene/Protein: CNDP2
- Product Description: Immunotag™ CNDP2 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | CNDP2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human CNDP2 |
| Specificity | CNDP2 Antibody detects endogenous levels of total CNDP2 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | CNDP2 |
| Accession No. | Q96KP4 |
| Alternate Names | 0610010E05Rik; C76600; Carnosinase , tissue; Carnosinase 2; CN 2; CN2; CNDP 2; CNDP dipeptidase 2 (metallopeptidase M20 family); CNDP dipeptidase 2; CNDP2; CNDP2_HUMAN; CPGL; Cytosolic non specific dipeptidase; Cytosolic non-specific dipeptidase; Cytosolic nonspecific dipeptidase; Dip-2; FLJ10830; FLJ35544; Glutamate carboxypeptidase like protein 1; Glutamate carboxypeptidase-like protein 1; HsT2298; Nonspecific dipeptidase, cutosolic; Pep-1; Pep1; PEPA; Peptidase A; |
| Description | Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly (PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation (PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells (PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis (PubMed:25964343). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 53kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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