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ITA9286

ITA9286-2
ITA9286-1
ITA9286-2
ITA9286-1
  • Gene/Protein: GAS8
  • Product Description: Immunotag™ GAS8 Antibody
  • 280.0000
    Price in reward points: 280

    Available Options

ITA9286

Immunotag™ GAS8 Antibody
Antibody Specification
Datasheet

Target Protein GAS8
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,ELISA
Recommended Dilution WB 1:1000-3000 IHC 1:200
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human GAS8
Specificity GAS8 Antibody detects endogenous levels of total GAS8
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name GAS8
Accession No. O95995
Alternate Names Growth arrest specific protein 8; MGC138326; GAS 11; GAS 8; GAS-11; GAS-8; GAS11; Gas8; GAS8_HUMAN; Growth arrest specific 11; Growth arrest specific 8; Growth arrest specific protein 11; Growth arrest-specific protein 11; Growth arrest-specific protein 8;
Description Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning (PubMed:26387594, PubMed:27120127, PubMed:27472056). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by faciltating the trafficking of SMO into the cilium and the stimulation of SMO activity in a GRK2-dependent manner (By similarity).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 56 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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