ITA9492
ITA9492
ITA9492
from
$526.00
Price in reward points: 526
- Catalog: ITA9492
- Gene/Protein: PIK3R6
- Product Description: Immunotag™ PIK3R6 Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein PIK3R6 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:1000-3000 Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen A synthesized peptide derived from human PIK3R6 Specificity PIK3R6 Antibody detects endogenous levels of total PIK3R6 Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name PIK3R6 Accession No. Q5UE93 Alternate Names C17orf38; Chromosome 17 open reading frame 38; HsT41028; p84 PI3K adapter protein; p84 PIKAP; p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein; p87 PI3K adapter protein; p87PIKAP; Phosphatidylinositol 3-kinase, regulatory subunit 6; Phosphoinositide 3-kinase gamma adapter protein of 87 kDa; Phosphoinositide 3-kinase regulatory subunit 6; PI3Kgamma adapter protein of 87 kDa; PI3R6_HUMAN; PIK3R6; Description Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 84 kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | PIK3R6 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human PIK3R6 |
| Specificity | PIK3R6 Antibody detects endogenous levels of total PIK3R6 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | PIK3R6 |
| Accession No. | Q5UE93 |
| Alternate Names | C17orf38; Chromosome 17 open reading frame 38; HsT41028; p84 PI3K adapter protein; p84 PIKAP; p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein; p87 PI3K adapter protein; p87PIKAP; Phosphatidylinositol 3-kinase, regulatory subunit 6; Phosphoinositide 3-kinase gamma adapter protein of 87 kDa; Phosphoinositide 3-kinase regulatory subunit 6; PI3Kgamma adapter protein of 87 kDa; PI3R6_HUMAN; PIK3R6; |
| Description | Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 84 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |