ITA9584
ITA9584
- Catalog: ITA9584
- Gene/Protein: RGS17
- Product Description: Immunotag™ RGS17 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | RGS17 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC,ELISA |
Recommended Dilution | WB 1:1000-3000 IHC 1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human RGS17 |
Specificity | RGS17 Antibody detects endogenous levels of total RGS17 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | RGS17 |
Accession No. | Q9UGC6 |
Alternate Names | hRGS17; Regulator of G protein signalling 17; Regulator of G protein signalling Z2; Regulator of G-protein signaling 17; RGS-17; RGS17; RGS17_HUMAN; RGSZ2; |
Description | Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 24 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |