ITA9604
ITA9604
ITA9604
from
$526.00
Price in reward points: 526
- Catalog: ITA9604
- Gene/Protein: ARHGEF4
- Product Description: Immunotag™ ARHGEF4 Antibody
-
Description
-
Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein ARHGEF4 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:1000-3000 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen A synthesized peptide derived from human ARHGEF4 Specificity ARHGEF4 Antibody detects endogenous levels of total ARHGEF4 Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name ARHGEF4 Accession No. Q9NR80 Alternate Names APC stimulated guanine nucleotide exchange factor 1; APC stimulated guanine nucleotide exchange factor; ARHGEF 4; Asef; ASEF1; GEF 4; GEF; GEF4; KIAA1112; Rho guanine nucleotide exchange factor (GEF) 4; Rho guanine nucleotide exchange factor 4; STM 6; STM6; Description Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 79 kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | ARHGEF4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human ARHGEF4 |
| Specificity | ARHGEF4 Antibody detects endogenous levels of total ARHGEF4 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | ARHGEF4 |
| Accession No. | Q9NR80 |
| Alternate Names | APC stimulated guanine nucleotide exchange factor 1; APC stimulated guanine nucleotide exchange factor; ARHGEF 4; Asef; ASEF1; GEF 4; GEF; GEF4; KIAA1112; Rho guanine nucleotide exchange factor (GEF) 4; Rho guanine nucleotide exchange factor 4; STM 6; STM6; |
| Description | Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 79 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |