ITA9731
ITA9731
- Catalog: ITA9731
- Gene/Protein: USP49
- Product Description: Immunotag™ USP49 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | USP49 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:1000-3000 IHC 1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human USP49 |
| Specificity | USP49 Antibody detects endogenous levels of total USP49 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | USP49 |
| Accession No. | Q70CQ1 |
| Alternate Names | Deubiquitinating enzyme 49; MGC20741; Ubiquitin carboxyl-terminal hydrolase 49; ubiquitin specific peptidase 49; Ubiquitin thiolesterase 49; Ubiquitin-specific-processing protease 49; UBP49; UBP49_HUMAN; USP49; USP49 ubiquitin specific peptidase 49; |
| Description | Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 79 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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