ITA9732
ITA9732
- Catalog: ITA9732
- Gene/Protein: USP51
- Product Description: Immunotag™ USP51 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | USP51 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:1000-3000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human USP51 |
Specificity | USP51 Antibody detects endogenous levels of total USP51 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | USP51 |
Accession No. | Q70EK9 |
Alternate Names | Deubiquitinating enzyme 51; Ubiquitin carboxyl-terminal hydrolase 51; Ubiquitin specific peptidase 51; Ubiquitin thioesterase 51; Ubiquitin thiolesterase 51; Ubiquitin-specific-processing protease 51; UBP51_HUMAN; USP51; |
Description | Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 80 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |