ITM0066
ITM0066
ITM0066
from
$556.00
Price in reward points: 556
- Catalog: ITM0066
- Gene/Protein: BLK
- Product Description: Immunotag™ Blk Monoclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein BLK Clonality Monoclonal Storage/Stability -20°C/1 year Application WB,IHC-p,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Mouse Immunogen Purified recombinant fragment of Blk expressed in E. Coli. Specificity Blk Monoclonal Antibody detects endogenous levels of Blk protein. Purification Affinity purification Form Ascitic fluid containing 0.03% sodium azide. Gene Name BLK Accession No. P51451 P16277 Alternate Names BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk Description BLK proto-oncogene, Src family tyrosine kinase(BLK) Homo sapiens This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010], Protein Expression Blood,Lymph,Primary B-Cells,Spleen, Subcellular Localization extrinsic component of cytoplasmic side of plasma membrane, Protein Function catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:May function in a signal transduction pathway that is restricted to B-lymphoid cells.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | BLK |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of Blk expressed in E. Coli. |
| Specificity | Blk Monoclonal Antibody detects endogenous levels of Blk protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | BLK |
| Accession No. | P51451 P16277 |
| Alternate Names | BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk |
| Description | BLK proto-oncogene, Src family tyrosine kinase(BLK) Homo sapiens This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010], |
| Protein Expression | Blood,Lymph,Primary B-Cells,Spleen, |
| Subcellular Localization | extrinsic component of cytoplasmic side of plasma membrane, |
| Protein Function | catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:May function in a signal transduction pathway that is restricted to B-lymphoid cells.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |