ITM0092
ITM0092
ITM0092
from
$556.00
Price in reward points: 556
- Catalog: ITM0092
- Gene/Protein: CSNK1A1
- Product Description: Immunotag™ Casein Kinase Iα Monoclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein Casein Kinase Iα Clonality Monoclonal Storage/Stability -20°C/1 year Application WB,IHC-p,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Mouse Immunogen Purified recombinant fragment of Casein Kinase Iα expressed in E. Coli. Specificity Casein Kinase Iα Monoclonal Antibody detects endogenous levels of Casein Kinase Iα protein. Purification Affinity purification Form Ascitic fluid containing 0.03% sodium azide. Gene Name CSNK1A1 Accession No. P48729 Q8BK63 Alternate Names CSNK1A1; Casein kinase I isoform alpha; CKI-alpha; CK1 Description catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex., Cell Pathway/ Category WNT,WNT-T CELLHedgehog, Protein Expression Brain,Epithelium,Liver,Lung,Placenta,Skin, Subcellular Localization condensed chromosome kinetochore,centrosome,cytosol,mRNA cleavage and polyadenylation specificity factor complex,membrane,nuclear speck,intracellular ribonucleoprotein complex,beta-catenin destruction complex,keratin filament,primary cilium, Protein Function catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | Casein Kinase Iα |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of Casein Kinase Iα expressed in E. Coli. |
| Specificity | Casein Kinase Iα Monoclonal Antibody detects endogenous levels of Casein Kinase Iα protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | CSNK1A1 |
| Accession No. | P48729 Q8BK63 |
| Alternate Names | CSNK1A1; Casein kinase I isoform alpha; CKI-alpha; CK1 |
| Description | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex., |
| Cell Pathway/ Category | WNT,WNT-T CELLHedgehog, |
| Protein Expression | Brain,Epithelium,Liver,Lung,Placenta,Skin, |
| Subcellular Localization | condensed chromosome kinetochore,centrosome,cytosol,mRNA cleavage and polyadenylation specificity factor complex,membrane,nuclear speck,intracellular ribonucleoprotein complex,beta-catenin destruction complex,keratin filament,primary cilium, |
| Protein Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |