ITM0162
ITM0162
ITM0162
from
$556.00
Price in reward points: 556
- Catalog: ITM0162
- Gene/Protein: COX4I1
- Product Description: Immunotag™ COX4 Monoclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein COX4 Clonality Monoclonal Storage/Stability -20°C/1 year Application WB,IF,FCM,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Rat,Monkey Host Species Mouse Immunogen Purified recombinant fragment of human COX4 expressed in E Coli Specificity COX4 Monoclonal Antibody detects endogenous levels of COX4 protein. Purification Affinity purification Form Ascitic fluid containing 0.03% sodium azide. Gene Name COX4I1 Accession No. P13073 P19783 P10888 Alternate Names COX4I1; COX4; Cytochrome c oxidase subunit 4 isoform 1; mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1 Description cytochrome c oxidase subunit 4I1(COX4I1) Homo sapiens Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes Cell Pathway/ Category Oxidative phosphorylation,Cardiac muscle contraction,Alzheimer's disease,Parkinson's disease,Huntington's disease, Protein Expression B-cell,Brain,Heart,Liver,Muscle,Ovary,Placenta,Pooled,Skeletal musc Subcellular Localization nucleus,mitochondrion,mitochondrial inner membrane,mitochondrial respiratory chain complex IV,membrane,integral component of membrane,extracellular exosome, Protein Function function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase IV family.,tissue specificity:Ubiquitous., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | COX4 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,FCM,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat,Monkey |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human COX4 expressed in E Coli |
| Specificity | COX4 Monoclonal Antibody detects endogenous levels of COX4 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | COX4I1 |
| Accession No. | P13073 P19783 P10888 |
| Alternate Names | COX4I1; COX4; Cytochrome c oxidase subunit 4 isoform 1; mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1 |
| Description | cytochrome c oxidase subunit 4I1(COX4I1) Homo sapiens Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes |
| Cell Pathway/ Category | Oxidative phosphorylation,Cardiac muscle contraction,Alzheimer's disease,Parkinson's disease,Huntington's disease, |
| Protein Expression | B-cell,Brain,Heart,Liver,Muscle,Ovary,Placenta,Pooled,Skeletal musc |
| Subcellular Localization | nucleus,mitochondrion,mitochondrial inner membrane,mitochondrial respiratory chain complex IV,membrane,integral component of membrane,extracellular exosome, |
| Protein Function | function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase IV family.,tissue specificity:Ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |