ITM0320
ITM0320
- Catalog: ITM0320
- Gene/Protein: GSTP1
- Product Description: Immunotag™ GSTP1 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | GSTP1 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,FCM,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human GSTP1 expressed in E. Coli. |
| Specificity | GSTP1 Monoclonal Antibody detects endogenous levels of GSTP1 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | GSTP1 |
| Accession No. | P09211 P19157 |
| Alternate Names | GSTP1; FAEES3; GST3; Glutathione S-transferase P; GST class-pi; GSTP1-1 |
| Description | glutathione S-transferase pi 1(GSTP1) Homo sapiens Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Glutathione metabolism,Metabolism of xenobiotics by cytochrome P450,Drug metabolism,Pathways in cancer,Prostate cancer, |
| Protein Expression | Brain,Cajal-Retzius cell,Colon carcinoma,Fetal brain cortex,Platelet,Urinar |
| Subcellular Localization | extracellular space,intracellular,nucleus,cytoplasm,mitochondrion,cytosol,plasma membrane,vesicle,extracellular exosome,TRAF2-GSTP1 complex, |
| Protein Function | catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the GST superfamily. Pi family.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,subunit:Homodimer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|