ITM0320
ITM0320
ITM0320
from
$556.00
Price in reward points: 556
- Catalog: ITM0320
- Gene/Protein: GSTP1
- Product Description: Immunotag™ GSTP1 Monoclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein GSTP1 Clonality Monoclonal Storage/Stability -20°C/1 year Application WB,IHC-p,IF,FCM,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Mouse Immunogen Purified recombinant fragment of human GSTP1 expressed in E. Coli. Specificity GSTP1 Monoclonal Antibody detects endogenous levels of GSTP1 protein. Purification Affinity purification Form Ascitic fluid containing 0.03% sodium azide. Gene Name GSTP1 Accession No. P09211 P19157 Alternate Names GSTP1; FAEES3; GST3; Glutathione S-transferase P; GST class-pi; GSTP1-1 Description glutathione S-transferase pi 1(GSTP1) Homo sapiens Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008], Cell Pathway/ Category Glutathione metabolism,Metabolism of xenobiotics by cytochrome P450,Drug metabolism,Pathways in cancer,Prostate cancer, Protein Expression Brain,Cajal-Retzius cell,Colon carcinoma,Fetal brain cortex,Platelet,Urinar Subcellular Localization extracellular space,intracellular,nucleus,cytoplasm,mitochondrion,cytosol,plasma membrane,vesicle,extracellular exosome,TRAF2-GSTP1 complex, Protein Function catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the GST superfamily. Pi family.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,subunit:Homodimer., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | GSTP1 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,FCM,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human GSTP1 expressed in E. Coli. |
| Specificity | GSTP1 Monoclonal Antibody detects endogenous levels of GSTP1 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | GSTP1 |
| Accession No. | P09211 P19157 |
| Alternate Names | GSTP1; FAEES3; GST3; Glutathione S-transferase P; GST class-pi; GSTP1-1 |
| Description | glutathione S-transferase pi 1(GSTP1) Homo sapiens Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Glutathione metabolism,Metabolism of xenobiotics by cytochrome P450,Drug metabolism,Pathways in cancer,Prostate cancer, |
| Protein Expression | Brain,Cajal-Retzius cell,Colon carcinoma,Fetal brain cortex,Platelet,Urinar |
| Subcellular Localization | extracellular space,intracellular,nucleus,cytoplasm,mitochondrion,cytosol,plasma membrane,vesicle,extracellular exosome,TRAF2-GSTP1 complex, |
| Protein Function | catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the GST superfamily. Pi family.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,subunit:Homodimer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |