ITM0560
ITM0560
ITM0560
from
$556.00
Price in reward points: 556
- Catalog: ITM0560
- Gene/Protein: RICTOR
- Product Description: Immunotag™ Rictor Monoclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein Rictor Clonality Monoclonal Storage/Stability -20°C/1 year Application WB,IHC-p,IF,FCM,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Monkey Host Species Mouse Immunogen Purified recombinant fragment of human Rictor expressed in E. Coli. Specificity Rictor Monoclonal Antibody detects endogenous levels of Rictor protein. Purification Affinity purification Form Ascitic fluid containing 0.03% sodium azide. Gene Name RICTOR Accession No. Q6R327 Q6QI06 Alternate Names RICTOR; KIAA1999; Rapamycin-insensitive companion of mTOR; AVO3 homolog; hAVO3 Description RPTOR independent companion of MTOR complex 2(RICTOR) Homo sapiens RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008], Cell Pathway/ Category mTOR, Protein Expression Amygdala,Brain,Epithelium,Lymph, Subcellular Localization cytosol,TORC2 complex, Protein Function function:Plays an essential role in embryonic growth and development (By similarity). Part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.,similarity:Belongs to the pianissimo family.,subunit:Forms part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to FRAP1 and PROTOR1 within the TORC2 complex. May interact with PROTOR2., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | Rictor |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,FCM,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Monkey |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human Rictor expressed in E. Coli. |
| Specificity | Rictor Monoclonal Antibody detects endogenous levels of Rictor protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | RICTOR |
| Accession No. | Q6R327 Q6QI06 |
| Alternate Names | RICTOR; KIAA1999; Rapamycin-insensitive companion of mTOR; AVO3 homolog; hAVO3 |
| Description | RPTOR independent companion of MTOR complex 2(RICTOR) Homo sapiens RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008], |
| Cell Pathway/ Category | mTOR, |
| Protein Expression | Amygdala,Brain,Epithelium,Lymph, |
| Subcellular Localization | cytosol,TORC2 complex, |
| Protein Function | function:Plays an essential role in embryonic growth and development (By similarity). Part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.,similarity:Belongs to the pianissimo family.,subunit:Forms part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to FRAP1 and PROTOR1 within the TORC2 complex. May interact with PROTOR2., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |