ITM0608
ITM0608
ITM0608
from
$556.00
Price in reward points: 556
- Catalog: ITM0608
- Gene/Protein: SYP
- Product Description: Immunotag™ SYP Monoclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein SYP Clonality Monoclonal Storage/Stability -20°C/1 year Application WB,IHC-p,ELISA Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Rat Host Species Mouse Immunogen Purified recombinant fragment of SYP expressed in E Coli Specificity SYP Monoclonal Antibody detects endogenous levels of SYP protein. Purification Affinity purification Form Ascitic fluid containing 0.03% sodium azide. Gene Name SYP Accession No. P08247 Q62277 P07825 Alternate Names SYP; Synaptophysin; Major synaptic vesicle protein p38 Description synaptophysin(SYP) Homo sapiens This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011], Protein Expression Brain, Subcellular Localization synaptic vesicle,membrane,integral component of membrane,cell junction,integral component of synaptic vesicle membrane,presynaptic membrane,neuron projection,terminal bouton,presynaptic active zone,excitatory synapse, Protein Function domain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.,function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.,online information:Synaptophysin entry,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the synaptophysin/synaptobrevin family.,similarity:Contains 1 MARVEL domain.,subunit:Homohexamer or homotetramer.,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | SYP |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of SYP expressed in E Coli |
| Specificity | SYP Monoclonal Antibody detects endogenous levels of SYP protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | SYP |
| Accession No. | P08247 Q62277 P07825 |
| Alternate Names | SYP; Synaptophysin; Major synaptic vesicle protein p38 |
| Description | synaptophysin(SYP) Homo sapiens This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011], |
| Protein Expression | Brain, |
| Subcellular Localization | synaptic vesicle,membrane,integral component of membrane,cell junction,integral component of synaptic vesicle membrane,presynaptic membrane,neuron projection,terminal bouton,presynaptic active zone,excitatory synapse, |
| Protein Function | domain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.,function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.,online information:Synaptophysin entry,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the synaptophysin/synaptobrevin family.,similarity:Contains 1 MARVEL domain.,subunit:Homohexamer or homotetramer.,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |