ITM1006
ITM1006
ITM1006
from
$556.00
Price in reward points: 556
- Catalog: ITM1006
- Gene/Protein: ALB
- Product Description: Immunotag™ ALB Monoclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein ALB Clonality Monoclonal Storage/Stability -20°C/1 year Application WB Recommended Dilution Western Blot: 1/1000 - 1/2000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human Host Species Mouse Immunogen Purified recombinant human ALB protein fragments expressed in E.coli. Specificity ALB Monoclonal Antibody detects endogenous levels of ALB protein. Purification Affinity purification Form Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol. Gene Name ALB Accession No. P02768 P07724 Alternate Names ALB; GIG20; GIG42; Serum albumin Description albumin(ALB) Homo sapiens This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016], Protein Expression Brain,Cajal-Retzius cell,Fetal brain cortex,Fetal liver,Heart,Liver,Platelet,Skeletal muscle,Urine, Subcellular Localization extracellular region,extracellular space,nucleus,endoplasmic reticulum,Golgi apparatus,platelet alpha granule lumen,myelin sheath,protein complex,extracellular exosome,blood microparticle, Protein Function caution:A peptide arising from positions 166 to 174 was originally (PubMed:3087352 and PubMed:2437111) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulates fat digestion, lipid absorption, and blood flow.,disease:A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood [MIM:194470].,disease:Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.,function:Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood.,miscellaneous:Acetylated on Lys-223 by acetylsalicylic acid.,online information:Serum albumin entry,polymorphism:The sequence shown is that of variant albumin A.,PTM:Glycated in diabetic patients.,PTM:Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.,similarity:Belongs to the ALB/AFP/VDB family.,similarity:Contains 3 albumin domains.,tissue specificity:Plasma., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | ALB |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB |
| Recommended Dilution | Western Blot: 1/1000 - 1/2000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant human ALB protein fragments expressed in E.coli. |
| Specificity | ALB Monoclonal Antibody detects endogenous levels of ALB protein. |
| Purification | Affinity purification |
| Form | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol. |
| Gene Name | ALB |
| Accession No. | P02768 P07724 |
| Alternate Names | ALB; GIG20; GIG42; Serum albumin |
| Description | albumin(ALB) Homo sapiens This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016], |
| Protein Expression | Brain,Cajal-Retzius cell,Fetal brain cortex,Fetal liver,Heart,Liver,Platelet,Skeletal muscle,Urine, |
| Subcellular Localization | extracellular region,extracellular space,nucleus,endoplasmic reticulum,Golgi apparatus,platelet alpha granule lumen,myelin sheath,protein complex,extracellular exosome,blood microparticle, |
| Protein Function | caution:A peptide arising from positions 166 to 174 was originally (PubMed:3087352 and PubMed:2437111) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulates fat digestion, lipid absorption, and blood flow.,disease:A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood [MIM:194470].,disease:Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.,function:Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood.,miscellaneous:Acetylated on Lys-223 by acetylsalicylic acid.,online information:Serum albumin entry,polymorphism:The sequence shown is that of variant albumin A.,PTM:Glycated in diabetic patients.,PTM:Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.,similarity:Belongs to the ALB/AFP/VDB family.,similarity:Contains 3 albumin domains.,tissue specificity:Plasma., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |