ITM1060
ITM1060
ITM1060
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- Catalog: ITM1060
- Gene/Protein: MAP2
- Product Description: Immunotag™ MAP-2 Monoclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein MAP-2 Clonality Monoclonal Storage/Stability -20°C/1 year Application WB Recommended Dilution Western Blot: 1/1000 - 1/2000. Not yet tested in other applications. Concentration 1 mg/ml Reactive Species Human,Mouse,Rat,Bovine,Dog Host Species Mouse Immunogen Purified recombinant human MAP-2 (C-terminus) protein fragments expressed in Ecoli Specificity MAP-2 Monoclonal Antibody detects endogenous levels of MAP-2 protein. Purification Affinity purification Form Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol. Gene Name MAP2 Accession No. P11137 P20357 P15146 Alternate Names MAP2; Microtubule-associated protein 2; MAP-2 Description microtubule associated protein 2(MAP2) Homo sapiens This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010], Protein Expression Brain,Brain cortex,Epithelium,Pancreas,Testis, Subcellular Localization nucleolus,cytoplasm,microtubule,microtubule associated complex,neuron projection, Protein Function Additional isoforms seem to exist,function:The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.,PTM:MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 Tau/MAP repeats.,similarity:Contains 4 Tau/MAP repeats., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | MAP-2 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB |
| Recommended Dilution | Western Blot: 1/1000 - 1/2000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat,Bovine,Dog |
| Host Species | Mouse |
| Immunogen | Purified recombinant human MAP-2 (C-terminus) protein fragments expressed in Ecoli |
| Specificity | MAP-2 Monoclonal Antibody detects endogenous levels of MAP-2 protein. |
| Purification | Affinity purification |
| Form | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol. |
| Gene Name | MAP2 |
| Accession No. | P11137 P20357 P15146 |
| Alternate Names | MAP2; Microtubule-associated protein 2; MAP-2 |
| Description | microtubule associated protein 2(MAP2) Homo sapiens This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010], |
| Protein Expression | Brain,Brain cortex,Epithelium,Pancreas,Testis, |
| Subcellular Localization | nucleolus,cytoplasm,microtubule,microtubule associated complex,neuron projection, |
| Protein Function | Additional isoforms seem to exist,function:The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.,PTM:MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 Tau/MAP repeats.,similarity:Contains 4 Tau/MAP repeats., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |