ITM1253
ITM1253
- Catalog: ITM1253
- Gene/Protein: nfic
- Product Description: Immunotag™ NFIC mouse mAb
405.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NFIC |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ICC |
Recommended Dilution | wb 1:200 icc 1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Mouse |
Immunogen | Purified recombinant human NFIC protein fragments expressed in E.coli. |
Specificity | This antibody detects endogenous levels of NFIC and does not cross-react with related proteins. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | nfic |
Accession No. | P08651 P70255 |
Alternate Names | 1110019L22Rik;1500041O16Rik;AA589446;AI746521;CAAT box transcription factor;CCAAT binding transcription factor;CCAAT box binding transcription factor;CCAAT-box-binding transcription factor;CNFI C;CTF;CTF5;MGC137374;MGC20153;NF I;NF I/C;NF-I/C;NF1 C;NF1-C; NF1C;NFI;NFI-C;NFI/C;NFIC;NFIC_HUMAN;Nuclear factor 1;Nuclear factor 1 C type;Nuclear factor 1 C-type;Nuclear factor 1/C;Nuclear factor I/C;TGGCA binding protein;TGGCA-binding protein;Transcription factor NFIC. |
Description | nuclear factor I C(NFIC) Homo sapiens The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011], |
Protein Expression | Epithelium,Uterus, |
Subcellular Localization | nucleus,nucleolus, |
Protein Function | function:Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.,similarity:Belongs to the CTF/NF-I family.,similarity:Contains 1 CTF/NF-I DNA-binding domain.,subunit:Binds DNA as a homodimer., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |