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ITM1342

ITM1342
  • Catalog: ITM1342
  • Gene/Protein: cbr1
  • Product Description: Immunotag™ CBR1 mouse mAb
405.0000
Price in reward points: 405

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Immunotag™ CBR1 mouse mAb
Antibody Specification
Datasheet
Target Protein CBR1
Clonality Monoclonal
Storage/Stability -20°C/1 year
Application WB,ICC
Recommended Dilution wb 1:1000 icc 1:100
Concentration 1 mg/ml
Reactive Species Human
Host Species Mouse
Immunogen Purified recombinant human CBR1 protein fragments expressed in E.coli
Specificity This antibody detects endogenous levels of CBR1 and does not cross-react with related proteins.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name cbr1
Accession No. P16152 P48758
Alternate Names 15 hydroxyprostaglandin dehydrogenase [NADP ];15-hydroxyprostaglandin dehydrogenase [NADP ];Carbonyl reductase [NADPH] 1;CBR 1;CBR1;CBR1_HUMAN;CRN;NADPH dependent carbonyl reductase 1;NADPH-dependent carbonyl reductase 1;Prostaglandin 9 ketoreductase; Prostaglandin 9-ketoreductase;Prostaglandin E(2) 9 reductase;Prostaglandin-E(2) 9-reductase;SDR21C1.
Description carbonyl reductase 1(CBR1) Homo sapiens The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013],
Cell Pathway/ Category Arachidonic acid metabolism,
Protein Expression Fetal brain,Mammary gland,Placenta,Skin,
Subcellular Localization cytosol,extracellular exosome,extracellular vesicle,
Protein Function catalytic activity:(13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NADP(+) = (13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADPH.,catalytic activity:(5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP(+) = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH.,catalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.,function:Catalyzes the reduction of a wide variety of carbonyl compounds including the antitumor anthracycline antibiotics. Can convert prostaglandin E2 to prostaglandin F2-alpha.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subunit:Monomer.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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