ITM1454
ITM1454
ITM1454
from
$447.00
Price in reward points: 447
- Catalog: ITM1454
- Gene/Protein: eif4ebp2
- Product Description: Immunotag™ 4E-BP2 mouse mAb
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein 4E-BP2 Clonality Monoclonal Storage/Stability -20°C/1 year Application WB Recommended Dilution wb dilution 1:1000 Concentration 1 mg/ml Reactive Species Transfected Host Species Mouse Immunogen Recombinant protein of human 4E-BP2. Specificity Transfected Only. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name eif4ebp2 Accession No. Q13542 P70445 Alternate Names 4E-BP2 ; 4EBP2 ; 4EBP2_HUMAN ; eIF4E binding protein 2 ; eIF4E-binding protein 2 ; Eif4ebp2 ; Eukaryotic translation initiation factor 4E binding protein 1 ; Eukaryotic translation initiation factor 4E-binding protein 2 ; PHASII ; phosphorylated, heat and acid stable regulated by insulin protein II. Description eukaryotic translation initiation factor 4E binding protein 2(EIF4EBP2) Homo sapiens This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008], Protein Expression Lung,Placenta,Uterus, Subcellular Localization intracellular,cytoplasm, Protein Function function:Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway.,PTM:Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF.,similarity:Belongs to the eIF4E-binding protein family.,subunit:Nonphosphorylated EIF4EBP2 interacts with EIF4E., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | 4E-BP2 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB |
| Recommended Dilution | wb dilution 1:1000 |
| Concentration | 1 mg/ml |
| Reactive Species | Transfected |
| Host Species | Mouse |
| Immunogen | Recombinant protein of human 4E-BP2. |
| Specificity | Transfected Only. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | eif4ebp2 |
| Accession No. | Q13542 P70445 |
| Alternate Names | 4E-BP2 ; 4EBP2 ; 4EBP2_HUMAN ; eIF4E binding protein 2 ; eIF4E-binding protein 2 ; Eif4ebp2 ; Eukaryotic translation initiation factor 4E binding protein 1 ; Eukaryotic translation initiation factor 4E-binding protein 2 ; PHASII ; phosphorylated, heat and acid stable regulated by insulin protein II. |
| Description | eukaryotic translation initiation factor 4E binding protein 2(EIF4EBP2) Homo sapiens This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008], |
| Protein Expression | Lung,Placenta,Uterus, |
| Subcellular Localization | intracellular,cytoplasm, |
| Protein Function | function:Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway.,PTM:Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF.,similarity:Belongs to the eIF4E-binding protein family.,subunit:Nonphosphorylated EIF4EBP2 interacts with EIF4E., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |