ITM3061
ITM3061
ITM3061
from
$447.00
Price in reward points: 447
- Catalog: ITM3061
- Gene/Protein: CEACAM5
- Product Description: Immunotag™ Carcinoembryonic Antigen Monoclonal Antibody(10E1)
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein CEA (10E1) Clonality Monoclonal Storage/Stability -20°C/1 year Application IHC-P,IF Recommended Dilution IHC 1:200 IF 1:50-200 Concentration 1 mg/ml Reactive Species Human Host Species Mouse Immunogen Synthetic Peptide of Carcinoembryonic Antigen Specificity The antibody detects endogenous CEA proteins. Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen Form PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Gene Name CEACAM5 Accession No. P06731 Q3UKK2 Alternate Names CEACAM5; CEA; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e Description carcinoembryonic antigen related cell adhesion molecule 5(CEACAM5) Homo sapiens This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015], Protein Expression Colon,Colon carcinoma,Liver,Saliva, Subcellular Localization integral component of plasma membrane,basolateral plasma membrane,anchored component of membrane,extracellular exosome,integral component of external side of plasma membrane, Protein Function function:Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.,PTM:Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 7 Ig-like (immunoglobulin-like) domains.,subunit:Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.,tissue specificity:Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | CEA (10E1) |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-P,IF |
| Recommended Dilution | IHC 1:200 IF 1:50-200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Synthetic Peptide of Carcinoembryonic Antigen |
| Specificity | The antibody detects endogenous CEA proteins. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | CEACAM5 |
| Accession No. | P06731 Q3UKK2 |
| Alternate Names | CEACAM5; CEA; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e |
| Description | carcinoembryonic antigen related cell adhesion molecule 5(CEACAM5) Homo sapiens This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015], |
| Protein Expression | Colon,Colon carcinoma,Liver,Saliva, |
| Subcellular Localization | integral component of plasma membrane,basolateral plasma membrane,anchored component of membrane,extracellular exosome,integral component of external side of plasma membrane, |
| Protein Function | function:Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.,PTM:Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 7 Ig-like (immunoglobulin-like) domains.,subunit:Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.,tissue specificity:Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |