ITM3378
ITM3378
ITM3378
from
$447.00
Price in reward points: 447
- Catalog: ITM3378
- Gene/Protein: HAO1
- Product Description: Immunotag™ HAO1 Monoclonal Antibody(Mix)
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein HAO1 (Mix) Clonality Monoclonal Storage/Stability -20°C/1 year Application WB,IHC-p,IF, Recommended Dilution WB: 1:1000-2000 IF 1:200 IHC 1:50-300 Concentration 1 mg/ml Reactive Species Mouse,Rat Host Species Mouse Immunogen Recombinant Protein of HAO1 Specificity The antibody detects endogenous HAO1 protein. Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen Form PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Gene Name HAO1 Accession No. Q9UJM8 Q9WU19 Alternate Names Hydroxyacid oxidase 1; HAOX1; Glycolate oxidase; GOX Description hydroxyacid oxidase 1(HAO1) Homo sapiens This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008], Cell Pathway/ Category Glyoxylate and dicarboxylate metabolism, Protein Expression Breast,Liver, Subcellular Localization peroxisome,peroxisomal matrix, Protein Function catalytic activity:(S)-2-hydroxy acid + O(2) = 2-oxo acid + H(2)O(2).,cofactor:FMN.,function:Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids.,pathway:Organic acid metabolism; glycolic acid degradation; 3-phospho-D-glyceric acid from glycolic acid: step 1/4.,similarity:Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.,similarity:Contains 1 FMN hydroxy acid dehydrogenase domain.,tissue specificity:Liver., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | HAO1 (Mix) |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF, |
| Recommended Dilution | WB: 1:1000-2000 IF 1:200 IHC 1:50-300 |
| Concentration | 1 mg/ml |
| Reactive Species | Mouse,Rat |
| Host Species | Mouse |
| Immunogen | Recombinant Protein of HAO1 |
| Specificity | The antibody detects endogenous HAO1 protein. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | HAO1 |
| Accession No. | Q9UJM8 Q9WU19 |
| Alternate Names | Hydroxyacid oxidase 1; HAOX1; Glycolate oxidase; GOX |
| Description | hydroxyacid oxidase 1(HAO1) Homo sapiens This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Glyoxylate and dicarboxylate metabolism, |
| Protein Expression | Breast,Liver, |
| Subcellular Localization | peroxisome,peroxisomal matrix, |
| Protein Function | catalytic activity:(S)-2-hydroxy acid + O(2) = 2-oxo acid + H(2)O(2).,cofactor:FMN.,function:Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids.,pathway:Organic acid metabolism; glycolic acid degradation; 3-phospho-D-glyceric acid from glycolic acid: step 1/4.,similarity:Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.,similarity:Contains 1 FMN hydroxy acid dehydrogenase domain.,tissue specificity:Liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |