ITM3394
ITM3394
ITM3394
from
$424.00
Price in reward points: 424
- Catalog: ITM3394
- Gene/Protein: NMBR
- Product Description: Immunotag™ NMBR Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein NMBR Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC-p Recommended Dilution WB: 1:1000-2000 IHC: 1:200-500 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthetic Peptide of NMBR Specificity The antibody detects endogenous NMBR protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Gene Name NMBR Accession No. P28336 O54799 P24053 Alternate Names NMBR; Neuromedin-B receptor; NMB-R; Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor Description neuromedin B receptor(NMBR) Homo sapiens This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016], Cell Pathway/ Category Neuroactive ligand-receptor interaction, Protein Expression G-protein coupled receptors, Subcellular Localization cytoplasm,plasma membrane,integral component of plasma membrane,integral component of membrane, Protein Function function:Receptor for neuromedin-B.,similarity:Belongs to the G-protein coupled receptor 1 family., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | NMBR |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p |
| Recommended Dilution | WB: 1:1000-2000 IHC: 1:200-500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of NMBR |
| Specificity | The antibody detects endogenous NMBR protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | NMBR |
| Accession No. | P28336 O54799 P24053 |
| Alternate Names | NMBR; Neuromedin-B receptor; NMB-R; Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor |
| Description | neuromedin B receptor(NMBR) Homo sapiens This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | G-protein coupled receptors, |
| Subcellular Localization | cytoplasm,plasma membrane,integral component of plasma membrane,integral component of membrane, |
| Protein Function | function:Receptor for neuromedin-B.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |