ITM3404
ITM3404
ITM3404
from
$424.00
Price in reward points: 424
- Catalog: ITM3404
- Gene/Protein: CACNG4
- Product Description: Immunotag™ L-type Ca++ CP γ4 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein L-type Ca++ CP γ4 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC-p Recommended Dilution WB: 1:1000-2000 IHC: 1:200-500 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthetic Peptide of L-type Ca++ CP γ4 Specificity The antibody detects endogenous L-type Ca++ CP γ4 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Gene Name CACNG4 Accession No. Q9UBN1 Q9JJV4 Q8VHW9 Alternate Names CACNG4; Voltage-dependent calcium channel gamma-4 subunit; Neuronal voltage-gated calcium channel gamma-4 subunit; Transmembrane AMPAR regulatory protein gamma-4; TARP gamma-4 Description calcium voltage-gated channel auxiliary subunit gamma 4(CACNG4) Homo sapiens The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010], Cell Pathway/ Category MAPK_ERK_Growth,MAPK_G_Protein,Cardiac muscle contraction,Hypertrophic cardiomyopathy (HCM),Arrhythmogenic right ventricular cardiomyopathy (ARVC),Dilated cardiomyopathy, Protein Expression Brain, Subcellular Localization plasma membrane,integral component of plasma membrane,voltage-gated calcium channel complex,endocytic vesicle membrane,AMPA glutamate receptor complex, Protein Function function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | L-type Ca++ CP γ4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p |
| Recommended Dilution | WB: 1:1000-2000 IHC: 1:200-500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of L-type Ca++ CP γ4 |
| Specificity | The antibody detects endogenous L-type Ca++ CP γ4 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | CACNG4 |
| Accession No. | Q9UBN1 Q9JJV4 Q8VHW9 |
| Alternate Names | CACNG4; Voltage-dependent calcium channel gamma-4 subunit; Neuronal voltage-gated calcium channel gamma-4 subunit; Transmembrane AMPAR regulatory protein gamma-4; TARP gamma-4 |
| Description | calcium voltage-gated channel auxiliary subunit gamma 4(CACNG4) Homo sapiens The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Cardiac muscle contraction,Hypertrophic cardiomyopathy (HCM),Arrhythmogenic right ventricular cardiomyopathy (ARVC),Dilated cardiomyopathy, |
| Protein Expression | Brain, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,voltage-gated calcium channel complex,endocytic vesicle membrane,AMPA glutamate receptor complex, |
| Protein Function | function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |