ITM3490
ITM3490
- Catalog: ITM3490
- Gene/Protein: Bombesin Rec. 2
- Product Description: Immunotag™ Bombesin Receptor 2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Bombesin Rec. 2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p |
| Recommended Dilution | WB: 1:500-1:2000, IHC: 1:100-1:300 EIA: 1:40000 |
| Concentration | 1 mg/ml |
| Reactive Species | Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of Bombesin Receptor 2 |
| Specificity | The antibody detects endogenous Bombesin Receptor 2 protein |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Gene Name | Bombesin Rec. 2 |
| Description | Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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