ITN0011
ITN0011
- Catalog: ITN0011
- Gene/Protein: PASK KIAA0135
- Product Description: Immunotag™ PASK Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PASK |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1100-1180 |
| Specificity | PASK Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PASK KIAA0135 |
| Accession No. | Q96RG2 Q8CEE6 |
| Description | PAS domain containing serine/threonine kinase(PASK) Homo sapiens This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011], |
| Protein Expression | Bone marrow,Brain,Cervix carcinoma,Epithelium,Eye,Lymph,Tes |
| Subcellular Localization | nucleus,cytoplasm,Golgi apparatus, |
| Protein Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by autophosphorylation on Thr-1161 and Thr-1165 and inhibited by the first PAS domain.,PTM:Autophosphorylated on Thr-1161 and Thr-1165.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,tissue specificity:Ubiquitously expressed, with slightly higher expression in brain, prostate and testis. Reduced expression was found in placenta., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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