ITN0061
ITN0061
- Catalog: ITN0061
- Gene/Protein: PDE3A
- Product Description: Immunotag™ PDE3A Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PDE3A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 250-330 |
| Specificity | PDE3A Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PDE3A |
| Accession No. | Q14432 Q9Z0X4 Q62865 |
| Description | phosphodiesterase 3A(PDE3A) Homo sapiens This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011], |
| Cell Pathway/ Category | Purine metabolism,Insulin_Receptor,Progesterone-mediated oocyte maturation, |
| Protein Expression | Blood,Epithelium,Liver,Myocardium,Penis,Platelet, |
| Subcellular Localization | cytosol,integral component of membrane, |
| Protein Function | catalytic activity:Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.,enzyme regulation:Inhibited by cGMP.,function:Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP).,online information:PDE3 entry,similarity:Belongs to the cyclic nucleotide phosphodiesterase family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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