ITN0085
ITN0085
- Catalog: ITN0085
- Gene/Protein: FSBP
- Product Description: Immunotag™ FSBP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FSBP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 110-190 |
| Specificity | FSBP Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | FSBP |
| Accession No. | O95073 Q8BKE5 D3ZXW3 |
| Description | disease:Defects in RAD54B may be a cause of tumor formation. Homozygous mutations at highly conserved position of RAD54B were observed in human primary lymphoma and colon cancer. These findings suggest that some cancers arise through defects of the RAD54B function.,function:Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect.,tissue specificity:Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon., |
| Protein Function | disease:Defects in RAD54B may be a cause of tumor formation. Homozygous mutations at highly conserved position of RAD54B were observed in human primary lymphoma and colon cancer. These findings suggest that some cancers arise through defects of the RAD54B function.,function:Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect.,tissue specificity:Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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