ITN0383
ITN0383
- Catalog: ITN0383
- Gene/Protein: RPL7A SURF-3 SURF3
- Product Description: Immunotag™ RL7A Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | RL7A |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 180-260 |
Specificity | RL7A Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | RPL7A SURF-3 SURF3 |
Accession No. | P62424 P12970 P62425 |
Description | ribosomal protein L7a(RPL7A) Homo sapiens Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene t |
Cell Pathway/ Category | Ribosome, |
Protein Expression | B-cell,Cerebellum,Eye,Lung,Placenta,Pooled,Skin,Uterus, |
Subcellular Localization | nucleus,nucleolus,cytoplasm,cytosol,ribosome,cell-cell adherens junction,focal adhesion,membrane,cytosolic large ribosomal subunit,polysomal ribosome,extracellular exosome, |
Protein Function | disease:Chromosomal recombination involving RPL7A activates the receptor kinase domain of the TRK oncogene.,similarity:Belongs to the ribosomal protein L7Ae family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |