ITN0554
ITN0554
- Catalog: ITN0554
- Gene/Protein: CPA6 CPAH
- Product Description: Immunotag™ CBPA6 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CBPA6 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | CBPA6 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | CPA6 CPAH |
Accession No. | Q8N4T0 Q5U901 |
Description | carboxypeptidase A6(CPA6) Homo sapiens The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome. [provided by RefSeq, May 2016], |
Protein Expression | Brain,Hematopoietic stem cell,Retina, |
Subcellular Localization | proteinaceous extracellular matrix,extracellular space, |
Protein Function | catalytic activity:Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.,cofactor:Binds 1 zinc ion per subunit.,disease:A chromosomal aberration disrupting CPA6 was found in a patient with Duane retraction syndrome (DURS) [MIM:126800]. Translocation t(6;8)(q26;q13).,similarity:Belongs to the peptidase M14 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |