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ITN0596

ITN0596
  • Catalog: ITN0596
  • Gene/Protein: KIF4B
  • Product Description: Immunotag™ KIF4B Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ KIF4B Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein KIF4B
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity KIF4B Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name KIF4B
Accession No. Q2VIQ3
Description kinesin family member 4B(KIF4B) Homo sapiens This gene is an intronless retrocopy of kinesin family member 4A. The protein encoded by this gene is a microtubule-based motor protein that plays vital roles in anaphase spindle dynamics and cytokinesis. [provided by RefSeq, Jul 2016],
Protein Expression Brain,Epithelium,Liver,Lymph,Lymphocyte,Muscle,Retinoblastoma,Testis,
Subcellular Localization nucleoplasm,cytosol,kinesin complex,microtubule,nuclear matrix,
Protein Function function:Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the kinesin-like protein family.,similarity:Belongs to the kinesin-like protein family. Chromokinesin subfamily.,similarity:Contains 1 kinesin-motor domain.,subcellular location:Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis.,subunit:Interacts with unphosphorylated PRC1 during late mitosis.,tissue specificity:Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung.,tissue specificity:Specifically expressed in testis.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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