ITN0630
ITN0630
- Catalog: ITN0630
- Gene/Protein: NCK1 NCK
- Product Description: Immunotag™ NCK1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NCK1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | NCK1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | NCK1 NCK |
| Accession No. | P16333 Q99M51 |
| Description | NCK adaptor protein 1(NCK1) Homo sapiens The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010], |
| Cell Pathway/ Category | ErbB_HER,Axon guidance,T_Cell_Receptor,Pathogenic Escherichia coli infection, |
| Protein Expression | Epithelium,Platelet,Uterus, |
| Subcellular Localization | protein phosphatase type 1 complex,nucleus,cytoplasm,endoplasmic reticulum,trans-Golgi network,cytosol,ribosome,plasma membrane,cell-cell junction,cell-cell adherens junction,vesicle membrane, |
| Protein Function | function:Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1.,PTM:Phosphorylated on Ser and Tyr residues.,similarity:Contains 1 SH2 domain.,similarity:Contains 3 SH3 domains.,subunit:Associates with BLNK, PLCG1, VAV1 and NCK1 in a B-cell antigen receptor-dependent fashion. Interacts with SOCS7. Part of a complex containing PPP1R15B, PP1 and NCK1. Interacts with RALGPS1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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