ITN0677
ITN0677
ITN0677
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$424.00
Price in reward points: 424
- Catalog: ITN0677
- Gene/Protein: HACE1 KIAA1320
- Product Description: Immunotag™ HACE1 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein HACE1 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized peptide derived from part region of human protein Specificity HACE1 Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name HACE1 KIAA1320 Accession No. Q8IYU2 Q3U0D9 D3ZBM7 Description HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1(HACE1) Homo sapiens This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016], Protein Expression Brain,Testis, Subcellular Localization Golgi membrane,nucleus,endoplasmic reticulum,Golgi cisterna membrane, Protein Function developmental stage:Expressed in fetal and pediatric kidney cells.,function:E3 ubiquitin-protein ligase that may function in cellular proteins degradation.,induction:Down-regulated in sporadic Wilms tumor.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 6 ANK repeats.,subcellular location:A significant portion localizes to the endoplasmic reticulum.,subunit:Interacts with the 26S proteasomal complex through the 20S core proteasomal subunit.,tissue specificity:Expressed in multiple tissues including heart, brain and kidney., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | HACE1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | HACE1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | HACE1 KIAA1320 |
| Accession No. | Q8IYU2 Q3U0D9 D3ZBM7 |
| Description | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1(HACE1) Homo sapiens This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016], |
| Protein Expression | Brain,Testis, |
| Subcellular Localization | Golgi membrane,nucleus,endoplasmic reticulum,Golgi cisterna membrane, |
| Protein Function | developmental stage:Expressed in fetal and pediatric kidney cells.,function:E3 ubiquitin-protein ligase that may function in cellular proteins degradation.,induction:Down-regulated in sporadic Wilms tumor.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 6 ANK repeats.,subcellular location:A significant portion localizes to the endoplasmic reticulum.,subunit:Interacts with the 26S proteasomal complex through the 20S core proteasomal subunit.,tissue specificity:Expressed in multiple tissues including heart, brain and kidney., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |