ITN0685
ITN0685
ITN0685
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- Catalog: ITN0685
- Gene/Protein: RNF41 FLRF NRDP1 SBBI03
- Product Description: Immunotag™ RNF41 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein RNF41 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse Host Species Rabbit Immunogen Synthesized peptide derived from part region of human protein Specificity RNF41 Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name RNF41 FLRF NRDP1 SBBI03 Accession No. Q9H4P4 Q8BH75 Description ring finger protein 41(RNF41) Homo sapiens This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011], Cell Pathway/ Category Endocytosis, Protein Expression Lymph,Lymphoblast, Subcellular Localization cytosol, Protein Function function:Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins, such as ERBB3.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 SIAH-type zinc finger.,subunit:Interacts with USP8 and ERBB3.,tissue specificity:Detected in ovary, testis and prostate., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | RNF41 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | RNF41 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | RNF41 FLRF NRDP1 SBBI03 |
| Accession No. | Q9H4P4 Q8BH75 |
| Description | ring finger protein 41(RNF41) Homo sapiens This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011], |
| Cell Pathway/ Category | Endocytosis, |
| Protein Expression | Lymph,Lymphoblast, |
| Subcellular Localization | cytosol, |
| Protein Function | function:Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins, such as ERBB3.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 SIAH-type zinc finger.,subunit:Interacts with USP8 and ERBB3.,tissue specificity:Detected in ovary, testis and prostate., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |