ITN0889
ITN0889
- Catalog: ITN0889
- Gene/Protein: MAL
- Product Description: Immunotag™ MAL Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | MAL |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 70-150 |
| Specificity | MAL Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | MAL |
| Accession No. | P21145 O09198 Q64349 |
| Description | mal, T-cell differentiation protein(MAL) Homo sapiens The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012], |
| Protein Expression | Brain,Lung,Lymphocyte,Placenta, |
| Subcellular Localization | endosome,endoplasmic reticulum,integral component of plasma membrane,integral component of membrane,apical plasma membrane,extrinsic component of membrane,membrane raft, |
| Protein Function | developmental stage:Expressed in the intermediate and late stages of T-cell differentiation.,function:Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function.,PTM:Lipoprotein.,similarity:Belongs to the MAL family.,similarity:Contains 1 MARVEL domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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