ITN0914
ITN0914
- Catalog: ITN0914
- Gene/Protein: ESCO1 EFO1 KIAA1911
- Product Description: Immunotag™ ESCO1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | ESCO1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 10-90 |
| Specificity | ESCO1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | ESCO1 EFO1 KIAA1911 |
| Accession No. | Q5FWF5 Q69Z69 |
| Description | establishment of sister chromatid cohesion N-acetyltransferase 1(ESCO1) Homo sapiens ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005 [PubMed 15958495]).[supplied by OMIM, Mar 2008], |
| Protein Expression | Bone marrow,Brain,Lymph,Mammary gland,Melan |
| Subcellular Localization | chromatin,nucleoplasm, |
| Protein Function | caution:It is uncertain whether Met-1 or Met-2 is the initiator.,domain:The N-terminal region seems to be responsible for the association with chromosomes, thus excluding any involvement of the Zn finger in this process.,function:Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase.,PTM:Phosphorylated during mitosis. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the acetyltransferase family. GCN5 subfamily.,subcellular location:Nuclear at interphase, associated with chromosomes during mitosis.,tissue specificity:Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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