ITN0915
ITN0915
- Catalog: ITN0915
- Gene/Protein: NNT
- Product Description: Immunotag™ NNTM Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | NNTM |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 240-320 |
| Specificity | NNTM Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | NNT |
| Accession No. | Q13423 Q61941 |
| Description | nicotinamide nucleotide transhydrogenase(NNT) Homo sapiens This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. [provided by RefSeq, Sep 2016], |
| Cell Pathway/ Category | Nicotinate and nicotinamide metabolism, |
| Protein Expression | Adrenal cortex,Heart,PCR rescued clones,Skeletal muscle, |
| Subcellular Localization | mitochondrion,mitochondrial inner membrane,mitochondrial respiratory chain,membrane,integral component of membrane, |
| Protein Function | catalytic activity:NADPH + NAD(+) = NADP(+) + NADH.,function:The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.,similarity:In the C-terminal section; belongs to the PNT beta subunit family.,similarity:In the N-terminal section; belongs to the AlaDH/PNT family.,subunit:Homodimer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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