ITN1044
ITN1044
ITN1044
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Price in reward points: 424
- Catalog: ITN1044
- Gene/Protein: PIGC GPI2
- Product Description: Immunotag™ PIGC Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein PIGC Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen Synthesized peptide derived from human protein, at AA range: 170-250 Specificity PIGC Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name PIGC GPI2 Accession No. Q92535 Q9CXR4 Q5PQQ4 Description phosphatidylinositol glycan anchor biosynthesis class C(PIGC) Homo sapiens This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized. [provided by RefSeq, Jul 2008], Cell Pathway/ Category Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Protein Expression Fibroblast,Lung, Subcellular Localization glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex,endoplasmic reticulum membrane,integral component of membrane, Protein Function catalytic activity:UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.,function:Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.,online information:Phosphatidylinositol N-acetylglucosaminyltransferase subunit C8,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGC family.,subunit:Associates with PIGA, PIGH, PIGP, PIGQ and DPM2. The latter is not essential for activity., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | PIGC |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 170-250 |
| Specificity | PIGC Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PIGC GPI2 |
| Accession No. | Q92535 Q9CXR4 Q5PQQ4 |
| Description | phosphatidylinositol glycan anchor biosynthesis class C(PIGC) Homo sapiens This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, |
| Protein Expression | Fibroblast,Lung, |
| Subcellular Localization | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex,endoplasmic reticulum membrane,integral component of membrane, |
| Protein Function | catalytic activity:UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.,function:Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.,online information:Phosphatidylinositol N-acetylglucosaminyltransferase subunit C8,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGC family.,subunit:Associates with PIGA, PIGH, PIGP, PIGQ and DPM2. The latter is not essential for activity., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |