ITN1044
ITN1044
- Catalog: ITN1044
- Gene/Protein: PIGC GPI2
- Product Description: Immunotag™ PIGC Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PIGC |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 170-250 |
Specificity | PIGC Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | PIGC GPI2 |
Accession No. | Q92535 Q9CXR4 Q5PQQ4 |
Description | phosphatidylinositol glycan anchor biosynthesis class C(PIGC) Homo sapiens This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, |
Protein Expression | Fibroblast,Lung, |
Subcellular Localization | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex,endoplasmic reticulum membrane,integral component of membrane, |
Protein Function | catalytic activity:UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.,function:Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.,online information:Phosphatidylinositol N-acetylglucosaminyltransferase subunit C8,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGC family.,subunit:Associates with PIGA, PIGH, PIGP, PIGQ and DPM2. The latter is not essential for activity., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |