ITN1051
ITN1051
- Catalog: ITN1051
- Gene/Protein: GPLD1 PIGPLD1
- Product Description: Immunotag™ PHLD Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PHLD |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 250-330 |
Specificity | PHLD Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | GPLD1 PIGPLD1 |
Accession No. | P80108 O70362 Q8R2H5 |
Description | glycosylphosphatidylinositol specific phospholipase D1(GPLD1) Homo sapiens Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, |
Protein Expression | Bone marrow,Eye,Liver,Pancreas,Plasma,Serum, |
Subcellular Localization | proteinaceous extracellular matrix,extracellular space,intracellular,cytoplasm,lysosomal membrane,intracellular membrane-bounded organelle,extracellular exosome, |
Protein Function | catalytic activity:6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(2)O = 6-(alpha-D-glucosaminyl)-1D-myo-inositol + phosphatidate.,function:This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane.,sequence caution:This sequence has numerous of conflicts with the human genome.,similarity:Belongs to the GPLD1 family.,similarity:Contains 4 FG-GAP repeats.,subunit:Monomer ., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |