ITN1110
ITN1110
- Catalog: ITN1110
- Gene/Protein: PPP1R3D PPP1R6
- Product Description: Immunotag™ PPR3D Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PPR3D |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 10-90 |
| Specificity | PPR3D Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PPP1R3D PPP1R6 |
| Accession No. | O95685 |
| Description | protein phosphatase 1 regulatory subunit 3D(PPP1R3D) Homo sapiens Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory. The level of phosphorylation is controlled by the opposing actions of protein kinases and protein phosphatases. Protein phosphatase 1 (PP1) is 1 of 4 major serine/threonine-specific protein phosphatases which have been identified in eukaryotic cells. PP1 associates with various regulatory subunits that dictate its subcellular localization and modulate its substrate specificity. Several subunits that target PP1 to glycogen have been identified. This gene encodes a glycogen-targeting subunit of PP1. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Insulin_Receptor, |
| Protein Expression | Brain,Lung,Platelet, |
| Subcellular Localization | glycogen granule,intracellular membrane-bounded organelle, |
| Protein Function | domain:The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.,function:Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.,similarity:Contains 1 CBM21 (carbohydrate binding type-21) domain.,subunit:Interacts with PPP1CC catalytic subunit of PP1, and associates with glycogen.,tissue specificity:Expressed in all tissue tested. High expression in skeletal muscle and heart., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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