ITN1154
ITN1154
- Catalog: ITN1154
- Gene/Protein: IQGAP2
- Product Description: Immunotag™ IQGA2 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | IQGA2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 200-280 |
Specificity | IQGA2 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | IQGAP2 |
Accession No. | Q13576 Q3UQ44 |
Description | IQ motif containing GTPase activating protein 2(IQGAP2) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Regulates Actin and Cytoskeleton, |
Protein Expression | Brain,Liver,Platelet, |
Subcellular Localization | cytoplasm,cytosol,microtubule,microvillus,cell surface,actin cytoskeleton,lamellipodium,filopodium,filamentous actin,extracellular exosome, |
Protein Function | function:Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 Ras-GAP domain.,similarity:Contains 1 WW domain.,similarity:Contains 3 IQ domains.,tissue specificity:Isoform 2 expression is enhanced in testis., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |