ITN1219
ITN1219
ITN1219
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$424.00
Price in reward points: 424
- Catalog: ITN1219
- Gene/Protein: ARHGAP5 RHOGAP5
- Product Description: Immunotag™ RHG05 Polyclonal Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein RHG05 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000 Concentration 1 mg/ml Reactive Species Human,Mouse Host Species Rabbit Immunogen Synthesized peptide derived from human protein . at AA range: 280-360 Specificity RHG05 Polyclonal Antibody detects endogenous levels of protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Gene Name ARHGAP5 RHOGAP5 Accession No. Q13017 P97393 Description Rho GTPase activating protein 5(ARHGAP5) Homo sapiens Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], Cell Pathway/ Category Focal adhesion,Leukocyte transendothelial migration, Protein Expression Brain,Inflammatory breast cancer,Mesangial cell,Pituitary adenoma,T Subcellular Localization intracellular,cytoplasm,endoplasmic reticulum,cytosol,membrane, Protein Function function:GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of p120GAP.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 4 FF domains.,subcellular location:Also membrane-associated when found in fibrillar patterns that colocalize with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin.,tissue specificity:Expressed in kidney, brain, liver and lung., Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet | |
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | RHG05 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 280-360 |
| Specificity | RHG05 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | ARHGAP5 RHOGAP5 |
| Accession No. | Q13017 P97393 |
| Description | Rho GTPase activating protein 5(ARHGAP5) Homo sapiens Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Focal adhesion,Leukocyte transendothelial migration, |
| Protein Expression | Brain,Inflammatory breast cancer,Mesangial cell,Pituitary adenoma,T |
| Subcellular Localization | intracellular,cytoplasm,endoplasmic reticulum,cytosol,membrane, |
| Protein Function | function:GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of p120GAP.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 4 FF domains.,subcellular location:Also membrane-associated when found in fibrillar patterns that colocalize with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin.,tissue specificity:Expressed in kidney, brain, liver and lung., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |