ITN1225
ITN1225
- Catalog: ITN1225
- Gene/Protein: RHPN2
- Product Description: Immunotag™ RHPN2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RHPN2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 110-190 |
| Specificity | RHPN2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | RHPN2 |
| Accession No. | Q8IUC4 Q8BWR8 |
| Description | rhophilin Rho GTPase binding protein 2(RHPN2) Homo sapiens This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009], |
| Protein Expression | Amygdala,Hippocampus,Kidney,Pituitary adenoma,Testis, |
| Subcellular Localization | nucleoplasm,cytoplasm,cytosol,intracellular membrane-bounded organelle,perinuclear region of cytoplasm, |
| Protein Function | function:Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.,induction:By thyrotropin (TSH). Regulated by the cAMP pathway.,similarity:Belongs to the RHPN family.,similarity:Contains 1 BRO1 domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 REM (Hr1) repeat.,subunit:Interacts with GTP-bound RhoA and RhoB. Interacts with both GTP- and GDP-bound RhoA. According to PubMed:12473120, it does not interact with RhoA. Interacts with KRT18.,tissue specificity:Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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