ITN1239
ITN1239
- Catalog: ITN1239
- Gene/Protein: RRBP1 KIAA1398
- Product Description: Immunotag™ RRBP1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RRBP1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1120-1200 |
| Specificity | RRBP1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | RRBP1 KIAA1398 |
| Accession No. | Q9P2E9 Q99PL5 |
| Description | ribosome binding protein 1(RRBP1) Homo sapiens This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012], |
| Protein Expression | Brain,Epithelium,Pancreas,Uterus, |
| Subcellular Localization | endoplasmic reticulum,ribosome,membrane,integral component of endoplasmic reticulum membrane, |
| Protein Function | Additional isoforms seem to exist. Additional isoforms are probable deriving from alternative splicing in the repeat region,function:Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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