ITN1240
ITN1240
- Catalog: ITN1240
- Gene/Protein: NQO2 NMOR2
- Product Description: Immunotag™ NQO2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NQO2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 40-120 |
| Specificity | NQO2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | NQO2 NMOR2 |
| Accession No. | P16083 Q9JI75 Q6AY80 |
| Description | NAD(P)H quinone dehydrogenase 2(NQO2) Homo sapiens This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014], |
| Protein Expression | Brain,Liver, |
| Subcellular Localization | nucleoplasm,cytoplasm,extracellular exosome, |
| Protein Function | catalytic activity:1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone.,cofactor:Binds 1 zinc ion per subunit.,cofactor:FAD.,enzyme regulation:Inhibited by melatonin, resveratrol and 5-hydroxytryptamine.,function:The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.,miscellaneous:Uses dihydronicotinamide riboside (NRH) rather than NAD(P)H as an electron donor.,similarity:Belongs to the NAD(P)H dehydrogenase (quinone) family.,subunit:Homodimer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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