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ITN1240

ITN1240
  • Gene/Protein: NQO2 NMOR2
  • Product Description: Immunotag™ NQO2 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ NQO2 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein NQO2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 40-120
Specificity NQO2 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name NQO2 NMOR2
Accession No. P16083 Q9JI75 Q6AY80
Description NAD(P)H quinone dehydrogenase 2(NQO2) Homo sapiens This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
Protein Expression Brain,Liver,
Subcellular Localization nucleoplasm,cytoplasm,extracellular exosome,
Protein Function catalytic activity:1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone.,cofactor:Binds 1 zinc ion per subunit.,cofactor:FAD.,enzyme regulation:Inhibited by melatonin, resveratrol and 5-hydroxytryptamine.,function:The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.,miscellaneous:Uses dihydronicotinamide riboside (NRH) rather than NAD(P)H as an electron donor.,similarity:Belongs to the NAD(P)H dehydrogenase (quinone) family.,subunit:Homodimer.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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